| Programs + Specialties |
|
| Training + Education |
University of Cape Town Faculty of Health Sciences, South Africa; Brigham and Women's Hospital; Massachusetts General Hospital; Yale-New Haven Hospital
|
| Board Certifications |
Maternal Fetal Medicine, Obstetrics and Gynecology |
| NPI # |
1760465819 |
| Gender |
Male |
| Accepted Insurances |
View Accepted Insurances at Tufts MC + Floating Hospital |
Tufts Medical Center
800 Washington St, #324
Boston, MA 02111
Phone #: 617-636-2382
Fax #: 617-636-8315
|
2017, Rochester General Hospital Association Teaching Fellowship, Department of OB/GYN, Rochester General Hospital, Rochester, NY
2011-present, Top Doctors in Boston
2011, The March of Dimes Award for Best Research in Prematurity at SMFM, San Francisco, CA
2011, Best Oral Presentation at SMFM, San Francisco, CA
2009, Best Doctors in Connecticut 2009-2010
2008, Best Oral Presentation at SMFM, Dallas, TX
2007, Fellow, American Gynecological and Obstetrical Society (AGOS)
2007-2011, America’s Top Obstetricians and Gynecologists, Consumer’s Research Council of America
2006-present, Fellow, Timothy Dwight College, Yale College, New Haven, CT
2006, The Charles A. Hunter Jr. Prize Thesis Award, 25th Annual Meeting of American Gynecological and Obstetrical Society, Williamsburg, VA
2006, The March of Dimes Award for the Best Research in Prematurity at SMFM, Miami, FL
2005-present, Best Doctors in America
2005, Best Poster Presentation at SMFM, Reno, NV
2004, The Zuspan Award for the Best Oral Presentation, Society for Obstetric Anesthesia and Perinatology (SOAP), Ft. Myers, FL
2003, Best Oral Presentation at SMFM, New Orleans, LA
2002, Best Oral Presentation at ACOG Distinct I Annual Meeting, Southampton, Bermuda
2001, Rochester General Hospital Association Teaching Fellowship, Department of OB/GYN, Rochester General Hospital, Rochester, NY
2000, Best Oral Presentation at the New England Perinatal Society, Manchester Village, VT
1999, Quest Diagnostics Award for Best Oral Presentation, The Endocrine Society, San Diego, CA
1999, Best Oral Presentation at New England Conference on Perinatal Research, Chatham, MA
1991, Best Poster Presentation at the 2nd European Congress on Prostaglandins in Reproduction, The Hague, the Netherlands
1988-1991, The Rhodes Scholarship (Southern Africa at Large), Oxford University, UK
Pavlicev M, Norwitz ER. Human parturition: nothing more than a delayed menstruation. Reprod Sci 2018;25:166-173.
van der Zwan A, Bi K, Norwitz ER, Crespo ÂC, Claas FHJ, Strominger JL, Tilburgs T. Mixed signature of activation and dysfunction allows human decidual CD8+ T cells to provide both tolerance and immunity. Proc Natl Acad Sci USA 2018;115:385-390.
Wang Y, Abrahams VM, Luo G, Norwitz NG, Snegovskikh VV, Ng SW, Norwitz ER. Progesterone inhibits apoptosis in fetal membranes by altering expression of both pro- and anti-angiogenic proteins. Reprod Sci 2018;1933719118759440;doi: 10.1177/1933719118759440.
Palmeiro-Silva YK, Orellana P, Venegas P, Monteiro L, Varas-Godoy M, Norwitz E, Rice G, Osorio E, Illanes SE. Effects of earthquake on perinatal outcomes: A Chilean register-based study. PLoS One 2018;13:e0191340.
Cross SN, Nelson RA, Potter JA, Norwitz ER, Abrahams VM. Magnesium sulfate differentially modulates fetal membrane inflammation in a time-dependent manner. Am J Reprod Immunol 2018;e12861; doi: 10.1371/journal.pone.0191340.
Pavlicev M, Norwitz ER. Human parturition: nothing more than a delayed menstruation. Reprod Sci 2018;25:166-173.
van der Zwan A, Bi K, Norwitz ER, Crespo ÂC, Claas FHJ, Strominger JL, Tilburgs T. Mixed signature of activation and dysfunction allows human decidual CD8+ T cells to provide both tolerance and immunity. Proc Natl Acad Sci USA 2018;115:385-390.
Wang Y, Abrahams VM, Luo G, Norwitz NG, Snegovskikh VV, Ng SW, Norwitz ER. Progesterone inhibits apoptosis in fetal membranes by altering expression of both pro- and anti-angiogenic proteins. Reprod Sci 2018;doi: 10.1177/1933719118759440.
Palmeiro-Silva YK, Orellana P, Venegas P, Monteiro L, Varas-Godoy M, Norwitz E, Rice G, Osorio E, Illanes SE. Effects of earthquake on perinatal outcomes: A Chilean register-based study. PLoS One 2018;13:e0191340.doi: 10.1371/journal.pone.0191340.
Tadesse S, Norwitz NG, Guller S, Arcuri F, Toti P, Norwitz ER, Kidane D. Dynamics of base excision repair at the maternal-fetal interface in pregnancies complicated by preeclampsia. Reprod Sci 2017;24:856-864.
Chen X, Li SL, Luo GY, Norwitz ER, Ouyang SY, Wen HX, Yuan Y, Tian XX, He JM. Ultrasono-graphic characteristics of cortical sulcus development in the human fetus between 18 and 41 weeks of gestation. Chin Med J 2017;130:920-928.
Taracanova A, Alevizos M, Karagkouni A, Weng Z, Norwitz E, Conti P, Leeman SE, Theoharides TC. SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors. Proc Natl Acad Sci USA 2017;114:e4002-4009.doi:10.1073/pnas.1524845114.
Snegovskikh D, Souza D, Walton Z, Dai F, Rachler R, Garay A, Snegovskikh VV, Braveman FR, Norwitz ER. Point-of-care viscoelastic testing improves the outcome of pregnancies complicated by severe postpartum hemorrhage. J Clin Anesth 2017;44:50-56.
Lee HJ, Park TC, Kim JH, Norwitz E, Lee B. The influence of oral dydrogesterone and vaginal progesterone on threatened abortion: a systematic review and meta-analysis. Biomed Res In 2017;3616875. doi: 10.1155/2017/3616875.
Lee SM, Park JS, Norwitz ER, Kim SM, Lee J, Park CW, Kim BJ, Jun JK.
Presenting Twins Are Exposed to Higher Levels of Inflammatory Mediators than
Nonpresenting Twins as Early as the Midtrimester of Pregnancy. PLoS One. 2015 Jun
15;10(6):e0125346. doi: 10.1371/journal.pone.0125346. eCollection 2015. PubMed
PMID: 26076029; PubMed Central PMCID: PMC4468219.
Norwitz ER, Bonney EA, Snegovskikh VV, Williams MA, Phillippe M, Park JS,
Abrahams VM. Molecular Regulation of Parturition: The Role of the Decidual Clock.
Cold Spring Harb Perspect Med. 2015 Apr 27. pii: a023143. doi:
10.1101/cshperspect.a023143. [Epub ahead of print] PubMed PMID: 25918180.
Norwitz ER. Clarifying when to recommend progesterone to prevent preterm
birth: clear as mud. BJOG. 2015 Jan;122(1):92. doi: 10.1111/1471-0528.13108. Epub
2014 Oct 7. PubMed PMID: 25289941.
Bakaysa SL, Potter JA, Hoang M, Han CS, Guller S, Norwitz ER, Abrahams VM.
Single- and double-stranded viral RNA generate distinct cytokine and antiviral
responses in human fetal membranes. Mol Hum Reprod. 2014 Jul;20(7):701-8. doi:
10.1093/molehr/gau028. Epub 2014 Apr 9. PubMed PMID: 24723465; PubMed Central
PMCID: PMC4072183.
Tadesse S, Kidane D, Guller S, Luo T, Norwitz NG, Arcuri F, Toti P, Norwitz
ER. In vivo and in vitro evidence for placental DNA damage in preeclampsia. PLoS
One. 2014 Jan 22;9(1):e86791. doi: 10.1371/journal.pone.0086791. eCollection
2014. PubMed PMID: 24466242; PubMed Central PMCID: PMC3899334.
Tadesse S, Luo G, Park JS, Kim BJ, Snegovskikh VV, Zheng T, Hodgson EJ,
Arcuri F, Toti P, Parikh CR, Guller S, Norwitz ER. Intra-amniotic infection
upregulates neutrophil gelatinase-associated lipocalin (NGAL) expression at the
maternal-fetal interface at term: implications for infection-related preterm
birth. Reprod Sci. 2011 Aug;18(8):713-22. doi: 10.1177/1933719110396722. Epub
2011 Mar 18. PubMed PMID: 21421891; PubMed Central PMCID: PMC3343092.
Snegovskikh VV, Bhandari V, Wright JR, Tadesse S, Morgan T, Macneill C,
Foyouzi N, Park JS, Wang Y, Norwitz ER. Surfactant protein-A (SP-A) selectively
inhibits prostaglandin F2alpha (PGF2alpha) production in term decidua:
implications for the onset of labor. J Clin Endocrinol Metab. 2011
Apr;96(4):E624-32. doi: 10.1210/jc.2010-1496. Epub 2011 Jan 26. PubMed PMID:
21270323; PubMed Central PMCID: PMC3070253.
Mesiano S, Wang Y, Norwitz ER. Progesterone receptors in the human pregnancy
uterus: do they hold the key to birth timing? Reprod Sci. 2011 Jan;18(1):6-19.
doi: 10.1177/1933719110382922. Epub 2010 Oct 1. Review. PubMed PMID: 20889955.
Lee HJ, Snegovskikh VV, Park JS, Foyouzi N, Han KT, Hodgson EJ, Guller S,
Norwitz ER. Role of GnRH-GnRH receptor signaling at the maternal-fetal interface.
Fertil Steril. 2010 Dec;94(7):2680-7. doi: 10.1016/j.fertnstert.2010.03.016. Epub
2010 Apr 18. PubMed PMID: 20400076.
Luo G, Abrahams VM, Tadesse S, Funai EF, Hodgson EJ, Gao J, Norwitz ER.
Progesterone inhibits basal and TNF-alpha-induced apoptosis in fetal membranes: a
novel mechanism to explain progesterone-mediated prevention of preterm birth.
Reprod Sci. 2010 Jun;17(6):532-9. doi: 10.1177/1933719110363618. Epub 2010 Apr 1.
PubMed PMID: 20360593.
Errol Norwitz, MD, is internationally recognized for his work in maternal-fetal medicine, particularly in the causes and prevention of preeclampsia and pre-term labor. His research includes the use of progesterone to delay preterm labor in high-risk women, the genetics of adverse pregnancy outcomes, and the molecular regulation of labor and delivery, both term and preterm. He is the Chair of Obstetrics and Gynecology at Tufts Medical Center, and a professor at Tufts University School of Medicine. He is board certified in Maternal Fetal Medicine and Obstetrics and Gynecology.
President, Pratt Ob/Gyn, Boston, MA
Medical Board, Tufts Medical Center, Boston, MA
Research Council, Tufts Medical Center, Boston, MA
Editor-in-Chief, Reviews in Obstetrics & Gynecology
2007-2010, Member, Obstetric Practice Committee, Yale-New Haven Hospital
2007-2010, Member, Gynecology Practice Committee, Yale-New Haven Hospital
2003-2010, Member, Quality Assessment Comm., Dept. of Ob/Gyn. & Repr. Biology, Yale-New Haven Hospital
2003, Chair, Mortality & Morbidity Conf., Dept. of Ob/Gyn. & Repr. Sciences, Yale-New Haven Hospital
NIH/NICHD (R01HD049446)
2011-2016
Innate Immune Responses of Trophoblasts in Pregnancy.
The major goals of this project are to determine the regulation of TLR-2 and TLR-8 mediated inflammation and apoptosis in the normal first trimester trophoblast in response to bacterial and viral components.
Role: Co-Investigator
NIH/NICHD (P01HD054713)
2009-2014
Program: Function of Toll-Like Receptors Throughout Gestation.
Project: Role of Toll-Like Receptors and Glucocorticoid in Placental-Fetal Inflammation.
The major goals of this project are to understand the function of Toll-like receptors at the maternal-fetal interface throughout gestation, and their role in infection-associated pregnancy complications. These studies will focus on the inflammatory
function of TLRs 3 and 4 in the first trimester placenta (Project I) and the inflammatory function of TLRs 2, 3 and 4 in the decidua (Project II) and term placenta (Project III).
Role: Co-Investigator
Burroughs Wellcome Fund
2009-2010
The Role of Placental Nod-Like Receptors in Infection-Associated Preterm Labor.
The major goals of this project are to determine the function of NLRs in the placenta and their role in infection-associated preterm labor.
Role: Co-Investigator
March of Dimes
2006-2010
Progesterone Receptor Dysregulation and Preterm Birth.
To understand in detail the molecular mechanisms by which progesterone supplementation can prevent preterm birth in some high-risk parturients and, in particular, to characterize the role of the progesterone receptor in spontaneous preterm labor.
Role: Principal Investigator.
Vision Grant Award (Panda)
2008-2009
Preeclampsia Foundation
Role of TLR in Preeclampsia.
The major goal of this project was to delineate the role of TLR in the pathogenesis of preeclampsia.
Role: Co-Investigator
NIH/NICHD (R01HD047321
2004-2010
A Proteomics Computational Approach to Preterm Delivery.
Uses proteomics and computational tools to classify pathogenetic entities within the preterm labor syndrome and identifies biomarkers with diagnostic and prognostic value.
Role: Co-Investigator
