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Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia
||AALL1131: A Phase III Randomized Trial for Newly Diagnosed High Risk B-Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum
||Michael J. Kelly, MD
This study will look at how effective different combinations of chemotherapy are a preventing acute lymphoblastic leukemia from coming back.
- Newly diagnosed B lymphoblastic leukemia
- Otherwise normal organ function
- No pregnant or nursing females
- No subjects with known Hepatitis B or C infection or history of cirrhosis
Subjects on this study will receive study intervention for about 2 ½ years. Subjects will come to the hospital for clinic visits, medical tests, and chemotherapy infusions just as often if they weren’t on this study. If they agree, subjects’ tissue (extra blood and bone marrow collected for clinical purposes) will be used for future research about cancer.
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